Identification of genes contributing to quantitative disease resistance in rice  

作　　者：KOU YanJun, LI XiangHua, XIAO JingHua & WANG ShiPing National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan),Huazhong Agricultural University, Wuhan 430070, China 

出　　处：《Science China(Life Sciences)》2010年第11期1263-1273,共11页中国科学（生命科学英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant No.30930063);the National Program of High Technology Development of China (Grant No.2006AA10A103)

摘　　要：Despite the importance of quantitative disease resistance during a plant’s life, little is known about the molecular basis of this type of host-pathogen interaction, because most of the genes underlying resistance quantitative trait loci (QTLs) are unknown. To identify genes contributing to resistance QTLs in rice, we analyzed the colocalization of a set of characterized rice defense-responsive genes and resistance QTLs against different pathogens. We also examined the expression patterns of these genes in response to pathogen infection in the parents of the mapping populations, based on the strategy of validation and functional analysis of the QTLs. The results suggest that defense-responsive genes are important resources of resistance QTLs in rice. OsWRKY45-1 is the gene contributing to a major resistance QTL.NRR,OsGH3-1,and OsGLP members on chromosome 8 contribute alone or collectively to different minor resistance QTLs. These genes function in a basal resistance pathway or in major disease resistance gene-mediated race-specific pathways.Despite the importance of quantitative disease resistance during a plant’s life, little is known about the molecular basis of this type of host-pathogen interaction, because most of the genes underlying resistance quantitative trait loci (QTLs) are unknown. To identify genes contributing to resistance QTLs in rice, we analyzed the colocalization of a set of characterized rice defense-responsive genes and resistance QTLs against different pathogens. We also examined the expression patterns of these genes in response to pathogen infection in the parents of the mapping populations, based on the strategy of validation and functional analysis of the QTLs. The results suggest that defense-responsive genes are important resources of resistance QTLs in rice. OsWRKY45-1 is the gene contributing to a major resistance QTL.NRR,OsGH3-1,and OsGLP members on chromosome 8 contribute alone or collectively to different minor resistance QTLs. These genes function in a basal resistance pathway or in major disease resistance gene-mediated race-specific pathways.

关 键 词：QUANTITATIVE disease resistance QTL defense-responsive gene RICE 

分 类 号：S511[农业科学—作物学]