Microarray analysis of gene expression profiles in the bovine mammary gland during lactation  

作　　者：HOU XiaoMing,LI QingZhang & HUANG TianYing Key Laboratory of Dairy Science of Education Ministry,Northeast Agricultural University,Harbin 150030,China 

出　　处：《Science China(Life Sciences)》2010年第2期248-256,共9页中国科学（生命科学英文版）

基　　金：supported by the National High Technology Research and Development Program of China (Grant No. 2006AA10Z1A4);the Innovation Team of the Northeast Agricultural University (Grant No. LXT005-1-1)

摘　　要：Mammary glands undergo functional and metabolic changes during virgin,lactation and dry periods.A total of 122 genes were identified as differentially expressed,including 79 up-regulated and 43 down-regulated genes during lactation compared with virgin and dry periods.Gene ontology analysis showed the functional classification of the up-regulated genes in lactation,including transport,biosynthetic process,signal transduction,catalytic activity,immune system process,cell death,and positive regulation of the developmental process.Microarray data clarified molecular events in bovine mammary gland lactation.Mammary glands undergo functional and metabolic changes during virgin,lactation and dry periods.A total of 122 genes were identified as differentially expressed,including 79 up-regulated and 43 down-regulated genes during lactation compared with virgin and dry periods.Gene ontology analysis showed the functional classification of the up-regulated genes in lactation,including transport,biosynthetic process,signal transduction,catalytic activity,immune system process,cell death,and positive regulation of the developmental process.Microarray data clarified molecular events in bovine mammary gland lactation.

关 键 词：MAMMARY GLAND microarray LACTATION GENOMICS gene expression profile 

分 类 号：Q78[生物学—分子生物学] S823[农业科学—畜牧学]