Pictet-Spengler condensation reactions catalyzed by a recyclable H^+-montmorillonite as a heterogeneous BrΦnsted acid  

作　　者：WANG YuFeng,SONG ZhanBo,CHEN ChunXia & PENG JinSong Department of Chemistry and Chemical Engineering,College of Science,Northeast Forestry University,Harbin 150040,China 

出　　处：《Science China Chemistry》2010年第3期561-567,共7页中国科学（化学英文版）

基　　金：support from a Grant-in-Aid for Young Teachers (Grant No 09025) from Northeast Forestry University;support by Grant-in-Aid for Young Scientists (Grant No 2008RFQXG012) from Harbin Science and Technology Bureau

摘　　要：Catalytic performance of different cation-exchanged montmorillonite clays has been investigated in the Pictet-Spengler C-C bond forming reaction.H+-Montmorillonite was found to be a very efficient and reusable catalyst for the endo cyclization of β-phenylethylamine derivatives with aldehydes under solvent-free conditions.In addition,an aqueous condensation version for the synthesis of tetrahydro-β-carbolines using the H+-montmorillonite catalyst has been developed.In these environmentally friendly processes,the use of organic solvents was avoided and the catalyst was recycled with maintenance of high catalytic activity.Catalytic performance of different cation-exchanged montmorillonite clays has been investigated in the Pictet-Spengler C-C bond forming reaction.H+-Montmorillonite was found to be a very efficient and reusable catalyst for the endo cyclization of β-phenylethylamine derivatives with aldehydes under solvent-free conditions.In addition,an aqueous condensation version for the synthesis of tetrahydro-β-carbolines using the H+-montmorillonite catalyst has been developed.In these environmentally friendly processes,the use of organic solvents was avoided and the catalyst was recycled with maintenance of high catalytic activity.

关 键 词：HETEROGENEOUS catalysis catalyst recycling MESOPOROUS materials green synthesis 

分 类 号：O643.3[理学—物理化学]