Direct palladium/copper oxidative cross-coupling of α-methylstyrene with acrylates  

作　　者：AL-MAKSOUD Walid DJAKOVITCH Laurent JAHJAH Mohamad PINEL Catherine 

机构地区：[1]Université de Lyon,CNRS,UMR 5256,IRCELYON,Institut de recherches sur la catalyse et l'environnement de Lyon

出　　处：《Science China Chemistry》2010年第9期1927-1931,共5页中国科学（化学英文版）

基　　金：the National Agency of Research (CATAQ N° ANR-07-CP2D-0167-01/02) for funding

摘　　要：Fully palladium/copper catalytic oxidative cross-coupling of acrylates with α-methylstyrene was performed in a DMSO/AcOH(1:1) mixture at 60℃ in the air.This improves previous procedures which employed stoichiometric amounts of copper and oxygen.Thus various acrylates were effectively coupled to α-methylstyrene giving the expected compounds in moderate to good yields(44%-65%) as a mixture of E and Z isomers.Fully palladium/copper catalytic oxidative cross-coupling of acrylates with α-methylstyrene was performed in a DMSO/AcOH(1:1) mixture at 60℃ in the air.This improves previous procedures which employed stoichiometric amounts of copper and oxygen.Thus various acrylates were effectively coupled to α-methylstyrene giving the expected compounds in moderate to good yields(44%-65%) as a mixture of E and Z isomers.

关 键 词：DIRECT CROSS-COUPLING oxidative couplings PALLADIUM COPPER catalytic procedures olefin CROSS-COUPLING 

分 类 号：O643.32[理学—物理化学]