Identifying non-neutral amino acid substitutions by SVMs  

作　　者：Shan Gao, Ning Zhang, Guang You Duan, Tao Zhang College of Life Science, Nankai University, Tianjin 300071, China 

出　　处：《生物物理学报》2009年第S1期17-18,共2页Acta Biophysica Sinica

基　　金：supported by the National Natural Science Foundation of China (30870827)

摘　　要：A substitution on an amino acid sequence can be defined as "intolerant" (non-neutral) or "tolerant" (neutral) according to whether or not it detectably alters protein phenotypes (e.g.,

关 键 词：nsSNPs MUTATION PREDICTION SVMS substitution-matrix 

分 类 号：Q51[生物学—生物化学]