人凝血酶原复合物离子交换树脂的筛选及吸附性能研究  

Selection of Ion Exchange Resin and Adsorption Performance for Human Prothrombin Complex Concentrates

作　　者：邱家山[1,2] 陈刚[1] 赵红卫[1] 何琦[3] 方为茂[1] 钟本和[1] 

机构地区：[1]四川大学化工学院,成都610065 [2]成都英德生物工程有限公司,成都610063 [3]中蓝晨光化工研究院,成都610041

出　　处：《生物技术通报》2009年第S1期340-344,共5页Biotechnology Bulletin

摘　　要：采用若干种人工合成的大孔阴离子交换树脂,对人血浆中凝血酶原复合物(PCC)的分离纯化性能进行了研究。同时,将DEAE-Sephadex A50对PCC的分离纯化性能与该类人工合成分离纯化材料进行了对比。研究结果表明,在各种人工合成大孔阴离子交换树脂中,CG-6对PCC具有较优的分离纯化性能;并系统研究了CG-6树脂对PCC分离纯化性能。The Separation and purification performance of human prothrombin complex concentrates were studied by use of several anion exchange resin.These experiments compare with the adsorption of DEAE-Sephadex A50.The results is that CG-6 has better adsorption performance for PCC.The adsorption performances of CG-6 for PCC were detailed studied.

关 键 词：大孔阴离子交换树脂 人凝血酶原复合物 分离纯化 

分 类 号：R96[医药卫生—药理学]