血清胆红素与冠心病的关系探讨  

Investigation on Association of Serum Bilirubin Concentration With Risk of Coronary Heart Disease

作　　者：黄宗清[1] 马京香[1] 刘文杰[2] 

机构地区：[1]山东省血液中心,济南250014 [2]山东中医药大学附院,济南250014

出　　处：《医学检验与临床》2003年第2期17-18,共2页Medical Laboratory Science and Clinics

摘　　要：目的 探讨血清胆红素浓度与冠心病(CHD)发生的危险性之间的关系。方法 观察79例CHD患者血清胆红素浓度,再据冠心病分型将其分为急性心肌梗死(AMI)组12例,不稳定型心绞痛(UAP)组37例,不稳定型心绞痛并心律失常组30例。同时观察30例健康体检组血清胆红素浓度。结果 冠心病组及不同类型冠心病组血清总胆红素、直接胆红素、间接胆红素浓度均隆低,与健康对照组比较均有显著性差异,而不同类型冠心病组间比较差异无显著性。结论 血清胆红素浓度与冠心病发生的危险性之间呈显著的负相关。Objective To investigate the relationship between serum bilirubin concentrations and risk of coronary heart desease (CHD). Methods Serum bilirubin concentrations were determined in 12 cases with acute myocardial infarction (AMI)、37 cases with unstable angina pectoris (UAP) and 30 cases with UAP with arrhythmia. Results The serum total bilirubin (TB)、 direct bilirubin (DB)、indirect bilirubin(IB) concentrations were lower in the three study groups of CHD than in the controls. There was significant difference between the patients with CHD and the controls. However, there was no significant difference among the three study groups of CHD. Conclusion Serum bilirubin concentrations was inversely and statistically significantly related to risk of CHD.

关 键 词：胆红素 抗氧化剂 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]