DNA疫苗的黏膜免疫  

Mucosal Immunization with DNA Vaccine

作　　者：邓明俊[1] 张彦明[1] 梁荣[1] 

机构地区：[1]西北农林科技大学动物科技学院,中国陕西杨凌712100

出　　处：《生命科学研究》2002年第S2期128-131,共4页Life Science Research

摘　　要：DNA做为一种新型的疫苗在免疫人和动物后可以引起强烈的体液免疫和细胞免疫.目前大多数DNA疫苗都是通过肌肉注射和基因枪肠道外途径免疫.然而通过黏膜途径免疫机体也可以得到有效的保护.现主要就DNA疫苗的黏膜免疫进展作一综述.DNA vaccine can induce potent humoral and celluar immune respondses in numerous animals. Most DNA vaccines have been administered parenterally.However,more effective protection against mucosal pathogens could be achieved with mucosal immunization. The use of DNA vaccine for the induction of mucosal immunity are reviewed.

关 键 词：DNA疫苗 黏膜系统 免疫应答 

分 类 号：R392[医药卫生—免疫学]