Microscopic elasticity imaging of vessel walls based on intravascular ultrasound  

作　　者：WAN Mingxi WANG Supin CUI Yaoyao LI Junbo LI Yangmei(Department of Biomedical Engineering, Xi’an Jiaotong University Xi’an 710049)Received Apr. 23, 2001 Revised Jun. 19, 2002 

出　　处：《Chinese Journal of Acoustics》2002年第4期307-316,共10页声学学报（英文版）

基　　金：This work was supported by the National Science Foundation of China(No.69925101,39970208).

摘　　要：The effect of the transducer eccentricity on grayscales of intravascualr ultrasound images was corrected based on the scattering properties of high frequency ultrasound in vessel walls. The displacement and strain distributions of vessel walls produced by tissue microelement motion were obtained using a novel motion estimation method in steps and sum based on the optical flow and genetic algorithm. Furthermore, authors firstly reconstructed 'real' elasticity distribution images of cross section tissues of vessel walls in the world. In vitro experimental results of porcine artery demonstrated the methods mentioned above are reasonable. Experimental investigation of vascular mechanics can be advanced to 2D sub-millimeter microstructure levels. These studies have potential to provide new technology means in monitoring and evaluation of Percutaneous transluminal coronary angioplasty process.The effect of the transducer eccentricity on grayscales of intravascualr ultrasound images was corrected based on the scattering properties of high frequency ultrasound in vessel walls. The displacement and strain distributions of vessel walls produced by tissue microelement motion were obtained using a novel motion estimation method in steps and sum based on the optical flow and genetic algorithm. Furthermore, authors firstly reconstructed 'real' elasticity distribution images of cross section tissues of vessel walls in the world. In vitro experimental results of porcine artery demonstrated the methods mentioned above are reasonable. Experimental investigation of vascular mechanics can be advanced to 2D sub-millimeter microstructure levels. These studies have potential to provide new technology means in monitoring and evaluation of Percutaneous transluminal coronary angioplasty process.

关 键 词：In IVUS Microscopic elasticity imaging of vessel walls based on intravascular ultrasound 

分 类 号：O426[理学—声学]