婴儿口服维生素K_1预防婴儿维生素K缺乏出血症的研究  

A Study on Effects of Infants Oral Vitamin K1 to Prevent VKDB

作　　者：周凤荣 何守森 王锡鲁 

机构地区：[1]山东省妇幼保健所,济南250014

出　　处：《中国病毒病杂志》2002年第1期9-11,共3页Chinese Journal of Viral Diseases

基　　金：山东省科技厅1998年科研基金(981216608)

摘　　要：目的 探讨预防婴儿维生素K缺乏性出血症的有效措施。方法 婴儿出生后即口服维生素K_1,每10天1次,每次2.5mg,共 10次,并采脐带血、1个月和 2个月静脉血,统一检测。结果 群体干预研究服药组维生素K缺乏性出血症发生率明显低于对照组(P<0.01)。小样本的实验室观察结果显示了口服组1个月和2个月静脉血维生素K缺乏诱导蛋白(PIVKA-Ⅱ)已经完全转阴。结论 婴儿口服维生素K_1能有效地预防典型及晚发性维生素K缺乏性出血症。Objective In order to look into the preventive measures of infant vitamin K deficiency bleeding (VKDB) . Methods Infants take vitamin K1 2.5mg/10days × 10 from birth; Neonatal umbilical cord blood and infant's vein blood one month and two month after taking vitamin K1 were collected respectively. Results The incidence of VKDB in preventive group was lower than that in the non- preventive group (P<0.01) .The infant's blood protein induced by vitamin K absence-Ⅱ (PTVKA- Ⅱ ) of oral group has already turned negative one month and two month after taking vitamin K1. Conclusion Vitamin K] taken by infants could prevent classical and late VKDB.

关 键 词：婴儿 维生素K缺乏/预防和控制 

分 类 号：R723[医药卫生—儿科]