Electrochemical determination of electroinactive guests of β-cyclodextrin at a self-assembled monolayer interface  

作　　者：鞠熀先 戴宗 DónalLeech 

出　　处：《Science China Chemistry》2002年第1期46-53,共8页中国科学（化学英文版）

基　　金：This work was supported by the National Natural Science Foundation of China (Grant No.29975013); the Doctoral Fund of the Ministry of Education of China (Grant No. 20000284033); the Natural Science Foundation of Jiangsu Province (Grant No. BK99030)

摘　　要：A novel determination method of electroinactive molecules by means of electrochemical technique is presented. A new self-assembled monolayer containing cyclodextrin (CD) is prepared with mono(6-o-p-tolylsulfonyl)-β-cyclodextrin. Although this derivatization process leads to a β-CD coverage of 10% of a full monolayer, this layer shows an effective host-guest response to ferrocene. The interfacial ferrocene complexation gives a response similar to that expected for a Langmuir adsorption isotherm yielding a stability constant of 4.2 ×104 mol-1· L and a maximum ferrocene coverage of 8.6×10-12 mol/cm2. The redox peak currents of the surface-confined ferrocene decrease upon addition of competing β-CD guest species to the solution, such as m-toluic acid (mTA) and sodium dodecyl sulfonate (SDS). This principle has been used for the determination of the electroinactive molecules, mTA and SDS in the concentration ranges of 0.8-2.7 μmol/L and 5-100 nmol/L, respectively.A novel determination method of electroinactive molecules by means of electrochemical technique is presented. A new self-assembled monolayer containing cyclodextrin (CD) is prepared with mono(6-o-p-tolylsulfonyl)-β-cyclodextrin. Although this derivatization process leads to a β-CD coverage of 10% of a full monolayer, this layer shows an effective host-guest response to ferrocene. The interfacial ferrocene complexation gives a response similar to that expected for a Langmuir adsorption isotherm yielding a stability constant of 4.2×104 mol-1.L and a maximum ferrocene coverage of 8.6×10-12 mol/cm2. The redox peak currents of the surfaceconfined ferrocene decrease upon addition of competing β-CD guest species to the solution, such as m-toluic acid (mTA) and sodium dodecyl sulfonate (SDS). This principle has been used for the determination of the electroinactive molecules, mTA and SDS in the concentration ranges of 0.8-2.7 μmol/L and 5–100 nmol/L, respectively.

关 键 词：VOLTAMMETRY self-assembled monolayer HOST-GUEST inclusional COMPLEXATION Β-CYCLODEXTRIN m-toluic acid sodium dodecyl sulfonate. 

分 类 号：O636[理学—高分子化学]