Structure Characterization of the Folding Intermediates of Proteins  

作　　者：周海梦 

出　　处：《Tsinghua Science and Technology》1999年第3期1524-1527,1596,共5页清华大学学报（自然科学版（英文版）

摘　　要：Although the native state and the fully unfolded state of proteins have been extensively studied, the folding pathway and intermediates in the protein folding process have not been thoroughly investigated. To understand the mechanisms of protein folding, the early intermediates in the protein folding process must be clearly characterized. The present paper is a mini review containing 20 references involving studies on folding intermediates of several proteins. Although the native state and the fully unfolded state of proteins have been extensively studied, the folding pathway and intermediates in the protein folding process have not been thoroughly investigated. To understand the mechanisms of protein folding, the early intermediates in the protein folding process must be clearly characterized. The present paper is a mini review containing 20 references involving studies on folding intermediates of several proteins.

关 键 词：protein FOLDING INTERMEDIATE CONFORMATION molten globular state 

分 类 号：Q51[生物学—生物化学]