Synthesis of a pair of novel receptors and their properties of enantioselective recognition for amino acid zwitterions  

作　　者：陆国元 刘芳 何卫江 王志林 胡宏纹 

出　　处：《Chinese Journal of Chemistry》1999年第5期508-515,427,共8页中国化学（英文版）

基　　金：National Natural Science Foundation of China.

摘　　要：A pair of artificial enantiotopic receptors la and lb composed of (S,S) or (R,R) chiral bicyclic guanidinium, azacrown ether and (t-butyldiphenylsilyloxy) methyl group for amino acid zwitterions have been synthesized. The liquid-liquid competition experiments and 1 H NMR studies indicate that the receptor 1a with (S, S) configuration and 1b with (R,R) configuration selectively recognize L- and D-aromatic amino acids & respectively.A pair of artificial enantiotopic receptors la and lb composed of (S,S) or (R,R) chiral bicyclic guanidinium, azacrown ether and (t-butyldiphenylsilyloxy) methyl group for amino acid zwitterions have been synthesized. The liquid-liquid competition experiments and 1 H NMR studies indicate that the receptor 1a with (S, S) configuration and 1b with (R,R) configuration selectively recognize L- and D-aromatic amino acids & respectively.

关 键 词：Enantioselective Recognition amino acid zwitterions artificial receptor 

分 类 号：O621[理学—有机化学]