Asymmetric 1,3-dipolar cycloaddition of nitrile oxides with optically active vinylboronic ester  

作　　者：姜标 张翱 阚颖 

机构地区：[1]Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》1999年第3期293-299,203,共7页中国化学（英文版）

基　　金：Project (No. 95QA14028) supported by the Star of Science;Technology Foundation of Shanghai.

摘　　要：Pinanyldioxy styrylboronic ester (1) was employed for asymmetric 1,3-dipolar cycloaddition with nitrile oxides, optically active Δ2-isoxazolines (3) or 4-hydroxy- Δ2-isoxazolines (4) were obtained. The effect of different bases on the selectivity of the cycloaddition reaction was studied.Pinanyldioxy styrylboronic ester (1) was employed for asymmetric 1,3-dipolar cycloaddition with nitrile oxides, optically active Δ2-isoxazolines (3) or 4-hydroxy- Δ2-isoxazolines (4) were obtained. The effect of different bases on the selectivity of the cycloaddition reaction was studied.

关 键 词：1 3-Dipolar cycloaddition vinylboronic ester Δ2-isaxazoline 4-hydroxy-Δ2-isoxazoline 

分 类 号：O621.2[理学—有机化学]