FD-1冷冻干燥机的研制及生物材料的冷冻干燥  

Development of a Freezing Drier for Lyophilization of Biomaterials

作　　者：吴志谷[1] 耿淼[1] 孙同柱[1] 付小兵[1] 熊德鑫[1] 乔迎伍[1] 宋月金[1] 孙世学[1] 盛志勇[1] 

机构地区：[1]解放军第304医院全军烧伤研究所基础部,北京100037

出　　处：《生物医学工程学杂志》2004年第3期460-463,共4页Journal of Biomedical Engineering

摘　　要：观察自制冷冻干燥机冷冻干燥生物材料的效果。采用 R5 0 2压缩机和制冷剂制成 FD- 1冷冻干燥机。本实验冷冻干燥了胶原海绵、菌种及去纤酶。在冻干箱负载或空载情况下蒸发冷凝器温度均可达到 - 4 5℃ ,小冰箱可达到 - 30℃ ,冻干的胶原海绵具有许多孔洞的结构 ,冻干的菌种和去纤酶性能保持良好。 FD-To observe and assess the performance and effect of our self-made FD-1 freezing drier on biomaterials. R502 compressor and R502 refrigerating agent were adopted. In the experiment, FD-1 lyophilized collagen sponge, strain and defibrinogenase. The evaporating-condenser temperature reached -45℃ and the small icebox temperature reached -30℃ under the loading or free-loading circumstances in the lyophilizing box. The lyophilized collagen sponge had many pores in the structure, and the strain and the defibrinogenase were lyophilized and maintained satisfactorily. This freezing drier is suitable for lyophilizing some biomaterial samples in small or medium batches.

关 键 词：冷冻干燥机 胶原海绵 菌种 生物材料 去纤酶 干燥效果 

分 类 号：TH789[机械工程—仪器科学与技术]