Continuous Ethanol Production Through Fermentation with Glucose and Xylose by Immobilized Yeasts in Two Cascade Fixed Beds  

作　　者：邓旭 岑沛霖 

机构地区：[1]Department of Chemical Engineering, Xiamen University [2]Department of Chemical Engineering, Zhejiang University

出　　处：《Chinese Journal of Chemical Engineering》1998年第1期54-62,共9页中国化学工程学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China.

摘　　要：Glucose and xylose were used as mixed carbon sources for ethanol production by a cascade immobi-lized-cell reactor.In the first fixed-bed reactor,immobilized S.cerevisiae was used to metabolize the glucoseanaerobically,and in the second fixed-bed column,the immobilized Pichia stipitis was applied to metabolize xy-lose aerobically.The effect of xylose on the glucose uptake by S.cerevisiae and the effect of ethanol on the xylosemetabolization by P.stipitis were studied.A mathematical model taking both tbe substrate and xylose inhibitioninto consideration was suggested for the description of the two-substrate fermentation process,and a total effec-tiveness factor η_s in the model was derived to take into account the mass transfer resistances of intra-particlesand liquid films.Calculated results are in fair agreement with the experimental data.Glucose and xylose were used as mixed carbon sources for ethanol production by a cascade immobi-lized-cell reactor. In the first fixed-bed reactor, immobilized S.cerevisiae was used to metabolize the glucose anaerobically, and in the second fixed-bed column, the immobilized Pichia stipitis was applied to metabolize xylose aerobically. The effect of xylose on the glucose uptake by S. cerevisiae and the effect of ethanol on the xylose metabolization by P. stipitis were studied. A mathematical model taking both the substrate and xylose inhibition into consideration was suggested for the description of the two-substrate fermentation process, and a total effectiveness factor ηs in the model was derived to take into account the mass transfer resistances of intra-particles and liquid films. Calculated results are in fair agreement with the experimental data.

关 键 词：ethanol CONTINUOUS FERMENTATION mixed substrate KINETIC model 

分 类 号：TQ223[化学工程—有机化工]