胰岛素抵抗与非胰岛素依赖型糖尿病继发冠心病关系的研究  

A study of insulin resistance for CHD followed as a complication of NIDDM

作　　者：马骏[1] 王正伦[1] 王建华[1] 

机构地区：[1]天津医科大学公共卫生学院,天津300070

出　　处：《中华疾病控制杂志》1997年第4期260-262,共3页Chinese Journal of Disease Control & Prevention

摘　　要：为研究非胰岛素依赖型糖尿病（NIDDM）继发冠心病（CHD）的危险因素，进行多个配比病例对照研究。通过条件Logistic回归分析；发现胰岛素抵抗及高血糖症是NIDDM继发CHD的危险因素OR分别为2．56（95％CI1．27～5．26）、4．32（95％CI2．56～7．28），高胰岛素血症增加NIDDM继发CHD的危险性，OR为1．60（95％CI1．03～2．47）。Coronay heart disease (CHD) is currently the leading cause of death among the diabetes population. In order t0 investigate the risk factors of clinical NIDDM with CHD, 102 cases of multiple group pair-matching case-control study were conducted. The results were obtained from conditional logistic regression analysis. The data showed that insulin rcsistance and hyperglycemia were risk factors causing secondary CHD. The higher of fasting blood glucose and the more serious insulin resistance, the higher risk of secondary CHD. And values of OR were 2. 56 (95%CI 1. 27～5. 26) and 4. 32 (95% CI 2. 56～7. 28) respectively. Hyperinsulinemia contributing to the risk of secondary CHD, OR was 1. 60 (95 % CI 1.03～2.47).

关 键 词：非胰岛素依赖型糖尿病 冠心病 胰岛素抵抗 条件LOGISTIC回归 

分 类 号：R587.1[医药卫生—内分泌]