溃疡病胃窦G和D细胞的体视学分析  

STEREOLOGICAL ANALYSIS OF G AND D CELLS IN THE GASRTIC ANTRUM OF PATIENTS WITH PEPTIC ULCER

作　　者：高增贺[1,2] 周济远[1,2] 任君旭[1,2] 郑慧娥 白雪梅[1,2] 张耕 王建伟[1,2] 徐根兴 

机构地区：[1]张家口医学院外科教研室组织学与胚胎学教研室 [2]南京大学生物教研室

出　　处：《中国组织化学与细胞化学杂志》1997年第1期106-111,共6页Chinese Journal of Histochemistry and Cytochemistry

基　　金：国家自然科学基金

摘　　要：应用真彩色医学院图像分析仪，对１５例ＤＵ、ＧＵ和ＣＯＮ组患者，非病变区胃窦粘膜，双重免疫组织化学显色的３００个Ｇ和Ｄ细胞进行形态学分析。每个细胞检测十二个参数。三组中，Ｇ细胞的周长、面积、长径、短径、比表面、平均截距、平均体积、平均面积、圆球度和平均直径数，在ＤＵ和ＧＵ组都发生改变，它们的显著性差异率分别为１００％；Ｄ细胞的长径、短径、形状因子和平均轴比数的改变，三组中的显著性差异率均在６０％以上，这些结果，进一步增加了溃疡病患者胃窦粘膜非病变区幽门腺Ｇ和Ｄ细胞的体视学形态计量学的参数资料。With color iamge analyser, 300 G and D cells were detected on double immunohistochemical staining sections of unaffected part of antral mucosa from 15 cases including the gastric ulcer (GU), duodenal ulcer (DU) and superficial gastritis as control group (Con). 12 parameters were measured. The data of perimeter, area, long diameter, short diameter, specific surface, mean intercept, mean volume, mean surface, sphericity and mean diameter of G cells wae varied in DU or GU groups as compared with Con group. The significant differential rate of G cells was 100% among three groups, respectively. The data of long diameter, short diameter, form factor PE and mean axial ratio of D cells showed significant differential rate above 60% among three groups, respectively. The results suggest that G and D cells participate in the rogulation of endecrine balance during peptic ulcer.

关 键 词：体视学 G细胞 D细胞 胃窦粘膜 溃疡病 

分 类 号：Q27[生物学—细胞生物学]