糖尿病肾病患者与正常人TXB2和PGF1α对照研究  

RELATIONSHIP OF PLASMA THROM-BOXANE B2, 6-KETO -PROSTAGLANDIN AND HYPERTENSIONIN PATIENTS WITH DIABETICNEPHROPATHY

作　　者：赵伟河[1] 梁君超[1] 胡肇衡[1] 史发明 

机构地区：[1]河南省荣康医院,北京医科大学人民医院内分泌科

出　　处：《中国民康医学》1995年第6期331-332,共2页Medical Journal of Chinese People’s Health

摘　　要：本文报告了１６２例不同阶段糖尿病肾病患者和正常人的血浆血栓素素Ｂ２（ＴＸＢ２）、６－酮一前列环素Ｆ１（ＰＧＦ）浓度。结果显示：ＴＸＢ２和ＴＸＢ２／ＰＧＦ１．随着糖尿病肾病程度加重逐渐升高，合并高血压者与血压正常者比较，ＴＸＢ２亦有显著升高；血压与ＴＸＢ２呈正相关。提示有效控制高血压对减缓糖尿病肾病微血管病变有临床意义。e measured the concentrations of plasmaTXB2 and 6-keto-PGF 1a in different periods ofrenal lesions of 162 diabetic patients. The resultsshowed that TXB2 and TXB2/PGF1a increased withthe exacerbation of diabetic nephropathy . TXB2 sig-nificantly increased in those complicated with thehrnertensioni the blood pressure had the positivecorrelation with TXB2. It suggested thatto effec-tively control the hypertension had the clinical sig-nificance in reducing micrangium lesion of diabeticnephropathy.

关 键 词：糖尿病 糖尿病肾病 血浆血栓素B2 6-酮-前列环素F1Α 

分 类 号：R587.2[医药卫生—内分泌]