THE INTERACTION OF Co（II）， Ni（II）， Cu（II） AND Zn（II） WITH 6－AMINOPENICILLANIC ACID IN AQUEOUS SOLUTION  

作　　者：Zhang, XD Guan, W Liu, QT Yang, P 

机构地区：[1]Liaoning Univ, Dept Chem, Shenyang 110036, Peoples R China [2]Shanxi Univ, Dept Chem, Taiyuan 030006, Peoples R China

出　　处：《Chinese Chemical Letters》1995年第6期531-532,共2页中国化学快报（英文版）

摘　　要：The complex formation equilibria of M2+ ions(M=Co,Ni,Cu,Zn) with 6-aminopenicillanic acid(6-APA)have been studied through potentiometric titrations. The results show that all of metal ions form 1:1 complexes(M(APA)+,N(APA)(OH)) with 6-APA in solution. Formation constants of the complexes were determined at 4O℃in aqueous solution having a fixed ionic Strength(0.1M NaClO4) and cormlated with the second-order rate constants for metal-ion Catalysed hydrolysis of peicillin.The complex formation equilibria of M2+ ions(M=Co,Ni,Cu,Zn) with 6-aminopenicillanic acid(6-APA)have been studied through potentiometric titrations. The results show that all of metal ions form 1:1 complexes(M(APA)+,N(APA)(OH)) with 6-APA in solution. Formation constants of the complexes were determined at 4O℃in aqueous solution having a fixed ionic Strength(0.1M NaClO4) and cormlated with the second-order rate constants for metal-ion Catalysed hydrolysis of peicillin.

分 类 号：O614.812[理学—无机化学]