RESOLUTION　OF　DL－α－AMINO　ACIDS　ON　A　L－HYDROXY　PROLINE　CHIRAL　PHASE　BY　LIGAND－EXCHANGE　CHROMATOGRAPHY  

作　　者：Tao CHEN  Tian Bao HUANG(Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041) 

出　　处：《Chinese Chemical Letters》1995年第5期383-384,共2页中国化学快报（英文版）

摘　　要：A HPLC bonded phase with L- hydroxy proline was prepared by coupling L-hydroxy proline as a chiral selector to silical gel via 3- glycidyloxypropyltrimethoxysilane. The chiral separations of 12 DL - amino acids on the chiral phase were performed and the effects of the chromatographic conditions,the pH of the mobile phase and the column temperature, on the resolution of DL-α-amino acids were studied.A HPLC bonded phase with L- hydroxy proline was prepared by coupling L-hydroxy proline as a chiral selector to silical gel via 3- glycidyloxypropyltrimethoxysilane. The chiral separations of 12 DL - amino acids on the chiral phase were performed and the effects of the chromatographic conditions,the pH of the mobile phase and the column temperature, on the resolution of DL-α-amino acids were studied.

关 键 词：DL OF RESOLUTION ACIDS AMINO 

分 类 号：O623[理学—有机化学]