植物血细胞凝集素对小鼠脾脏淋巴细胞γ－谷氨酰基转肽酶活性的影响  

THE INFLUENCE OF PHYTOHEMAGGLUTININ (PHA) ON γ-GLUTAMYLTRANSPEPTIDASE(γ-GT)ACTIVITY IN THE SPLENIC LYMPH CELLS OF MOUSE

作　　者：孔力[1] 安广宇[1] 闫晓红[1] 苏秀兰[1] 孟庆宝 王雪峰 舍英[1] 

机构地区：[1]内蒙古医学院细胞化学研究室,内蒙古蒙医学院,内蒙哲盟卫校

出　　处：《中国组织化学与细胞化学杂志》1995年第2期223-226,共4页Chinese Journal of Histochemistry and Cytochemistry

摘　　要：本文就植物血细胞凝集素（ＰＨＡ）作用的不同时间对小鼠脾脏淋巴细胞γ－谷氨酰基转肽酶（γ－ＧＴ）活性的影响进行了观察。结果表明，脾脏淋巴细胞转化率随给予ＰＨＡ时间的延长而上升，对照组＜２４ｈ组＜４８ｈ组＜７２ｈ组；淋巴细胞γ－ＧＴ活性于２４ｈ明显强于对照组（Ｐ＜０．００１），随着ＰＨＡ作用时间的延长其γ－ＧＴ活性逐渐下降，即４８ｈ组与对照组已无显著差异，而７２ｈ组却低于对照组（Ｐ＜０．００１）。可见ＰＨＡ在小鼠体内对γ－ＧＴ活性有很大影响。The influence of PHA ON γ-GT activity in different acting time was observed.The results showed that the transformation rate of splenic lymph cells increased with the prolonganon of PHA action time, i.e.the control group<24h group<48h group<72h group.Theactivity of γ-GT in the 24h group was obviously higher than that in the control group (P<0. 01).With the prolongation of the acting time of PHA,the activity of γ-GT was graduallydeclined. There was no significant difference between 48h group and control group,and theγ-GT of 72h group was lower than that of the control group (P<0.001).Thus it was concluded that PHA had a great influence on the γ-GT activity of mouse splenic Lymphcytes.

关 键 词：植物血细胞凝集素 细胞化学 γ-谷氨酰基转肽酶 

分 类 号：Q26[生物学—细胞生物学]