Effect of Repeated Low Frequency Stimulation on Content of Neuropeptides in Rat Spinal Ganglion  

作　　者：曲瑞瑶 吕国蔚 何国瑞 何京延 

机构地区：[1]Department of Neurobiology, Capital Institute of Medicine, Beijing 100054, PRC

出　　处：《Chinese Science Bulletin》1994年第14期1215-1219,共5页

摘　　要：Substance P (SP) and vasoactive intestinal peptide (VIP) are neuropeptides synthesized in the dorsal root ganglion (DRG). These neuropeptides diffuse toward the central nervous system and peripheral nerve endings. It is now recognized that almost all the SP-containing DRG cells are small-sized (type B), accounting for 20% of total DRG cell population. SP is thought to be neurotransmitters involved in noxious information transmission for primary sensory afferent fibers, while VIP is also involved in sensory modulation. DRG is defined by Sherrington as the 'Laterally Located Brain', and recently is also called The Brain of Spinal Motion Segment and The Mediator of Low Back Pain. Much attention

关 键 词：DORSAL root GANGLION repeated low frequency STIMULATION compound action potential immunologically active neuropeptide. 

分 类 号：R681[医药卫生—骨科学]