手术创伤对新生儿甲状腺内分泌功能的影响  

THE INFLUENCE OF SURGICAL OPERATIONS ON THE THYROID ENDOCRINE FUNCTION IN THE NEWBORN

作　　者：王春喜[1] 李思脱 崔瑞耀[2] 吴琍[1] 

机构地区：[1]青岛医学院附属医院小儿外科 [2]青岛医学院附属医院病理生理教研室

出　　处：《中国新生儿科杂志》1994年第3期114-115,144-145,共4页Chinese Journal of Neonatology

摘　　要：In order to find out the influence of surgical operation on the thyroid endocrine functionin the newbons, the levels of serum T,, T4 and rT, of 30 newbrons who received surgerywere determined before and after operations by radioimmunoassay. The results of this studyshowed that the postoperative levels of T3 and T4 reduced significantly (P<0.01), while thepostoperative levei of r, increased obviously (P<0. 01 ). All changes of postoperative thy-roid hormone returned to normal in about 7 days. At the same time, it was found that a per-sistent low level of T’ after operation indicated a poor prognosis and 3ignificant low level ofT, indicated a 8erious illness ; and there was a hlgh mortality (67% ) if the leveI of T’ was be-low 65ng/ml and the level of T, was below o. 5ng/ml. This study suggests that the determi-nations of T, and T’ indicate seriousness and forcast the progno8is of patients who receivedIn order to find out the influence of surgical operation on the thyroid endocrine functionin the newbons, the levels of serum T,, T4 and rT, of 30 newbrons who received surgerywere determined before and after operations by radioimmunoassay. The results of this studyshowed that the postoperative levels of T3 and T4 reduced significantly (P<0.01), while thepostoperative levei of r, increased obviously (P<0. 01 ). All changes of postoperative thy-roid hormone returned to normal in about 7 days. At the same time, it was found that a per-sistent low level of T' after operation indicated a poor prognosis and 3ignificant low level ofT, indicated a 8erious illness ; and there was a hlgh mortality (67% ) if the leveI of T' was be-low 65ng/ml and the level of T, was below o. 5ng/ml. This study suggests that the determi-nations of T, and T' indicate seriousness and forcast the progno8is of patients who received surgery

关 键 词：血清甲状腺激素 内分泌功能 手术创伤 甲状腺功能 甲状腺激素水平 新生儿生长发育 应激反应 围手术期 促甲状腺激素(TSH) 小儿外科 

分 类 号：R722.1[医药卫生—儿科]