心肌血管再建术后心肌营养情况的研究  

Myocardial Nutrition Study after Myocardial Revascu-Larization by Laser.

作　　者：董蓉[1] 郑道声[1] 包世宏[1] 张世华[1] 盖保康[1] 

机构地区：[1]上海第二医科大学附属仁济医院心内科,200001

出　　处：《中国介入心脏病学杂志》1994年第0期26-29,50,共5页Chinese Journal of Interventional Cardiology

摘　　要：本实验在10只新西兰兔的活体心脏上,用Nd—YAG激光打孔后,结扎冠状动脉前降支;4只仅做前降支结扎.分别于术后3周、5周处死动物.在距激光孔道0—2mm,2— 4mm,及4—6mm等处的左室前壁心肌上共取标本30块.而仅结扎前降支兔于3周,5周处取10块,正常兔左室前壁心肌取标本20块.以虫荧光素法测量心肌组织中三磷酸腺苷(ATP),磷酸肌酸(CP)含量.发现术后3周激光孔道附近心肌组织中的ATP已接近正常心肌组织中的ATP含量(P>0.05),术后5周远离孔道部的ATP已较3周时有所恢复,但仍较正常低.CP较ATP恢复慢.表明:心肌血管再建术的确可起到心肌营养的作用.The myocardial nutrition after myocardial revascu-larization was studied in 14 rabbits with the aid of Nd-YAG laser, before Ligation of the anterior descending branch of the left coronary artery (only ligated LAD in 4 rabbit), the rabbits were seperatively Killed 3 or 5 weekafter operating. Myocardial samples were abtained in the parti of 0 - 2,2 - 4,4 - 6mm from laser hole. Sample numbers were 30 in myocardial revascularization group (MRG); 20 in myocardial Infarction group(MIG); 20 in normal group (NG). Amount of ATP and CP in myocar-dia were determined with luciferase. Resalts.ATP and CP near laser holes were normal 3 week late. This far from laser holes was lower than that of normal myocardia 5 week late. Recover of CP amount was slower than that of ATP amount. Inclusion, myocardial revascularization can play role in myocardial nutrition.

关 键 词：激光心肌血管再建术 ATP CP 

分 类 号：R542.22[医药卫生—心血管疾病]