Ⅱ型糖尿病患者肾素－血管紧张素系统和激肽－前列腺素－血栓素系统的相互作用研究  

A study on the interaction between renin-angiotensin system and kinin-prostaglandins system in type Ⅱdiabetics

作　　者：冯波[1] 金之欣[1] 

机构地区：[1]同济医科大学附属同济医院内分泌研究室,湖北省宜昌市中心医院内分泌科

出　　处：《中国糖尿病杂志》1994年第1期22-25,65,共5页Chinese Journal of Diabetes

摘　　要：对４９例Ⅱ型糖尿病患者血清和１２小时过夜尿各项指标进行观测。结果：Ⅱ型糖尿病患者有明显的肾素－血管紧张素系统及激肽－前列腺素－血栓素系统调节障碍，此与糖尿病肾病发生有关，肾内激肽－前列腺素系统参与介导Ｃａｐｔｏｐｒｉｌ降低糖尿病肾病性蛋白尿的作用。A study of the various parameters of serum and 12-hour overnight urine in 49 patients with NIDDM showed that there was a significant regulatory abnormality of renin-angiotensin system and kinin-prostaglandins system in NIDDM patints with diabetic nephropathy and effect of captopril on reducing proteinuria was mediated by renal kinin-prostaglandins system.

关 键 词：糖尿病 前列腺素 缓激肽 血管紧张素转换酶类 

分 类 号：R587.1[医药卫生—内分泌]