舒脑宁治疗高原缺血性脑血管病的临床研究  

A CLINI CAL STUDY OF THERAPEUTIC EFFECTIVENESS IN TREATING IS CHEMIC CEREBROVASCULAR DISEASE WITH ISCHELIUM AT HIGH ALTITUDE

作　　者：吴世政[1] 王莉[1] 胡全中[1] 候倩 张海明[1] 顾浩平[1] 

机构地区：[1]青海省人民医院神经科,青海省人民医院呼吸科

出　　处：《高原医学杂志》1994年第2期22-25,共4页Journal of High Altitude Medicine

摘　　要：本文对舒脑宁（二氢麦角毒碱）治疗高原缺血性脑血管病进行了临床研究，随机选取６０例病例，其中口服舒脑宁治疗组４０例，对照组２０例，全部病例均按全国第二届脑血管病会议制定的诊断标准诊断，观察用药前后的临床疗效、血液流变学变化，以及部分病例的动脉血、脑脊液的氧分压、氧饱和度同步监测的改变。结果表明：总有效率为９２．５％，显效率７２．５％，对意识障碍、失语、短时记忆减退、偏瘫疗效显著，全血粘度、全血还原粘度、红细胞压积、血沉方程Ｋ值、血沉明显改善，脑脊液的氧分压、氧饱和度较前提高，认为，舒脑宁是治疗高原缺血性脑血管病较为理想的药物。he investigation selected 60 cases high altitude ischemic cere- brovascular disease and di-vided them into treated group(n= 40) and control group(n = 20)at random. The patients weregiven Ischelium in the treated group. There was no significant diff-erence between the twogroups in age,sex,state of illness,time of medication. anamnesis and complications. The resultsshowed that the overall effective rate was 92.5%。the markedly effecti-veness rate was 72.5%. The the rapeutic effectiveness was satis factory in treating cerebral function obstruction. Hemer-rheolohy,PaO_2and SaO_2C of cerebrospinal fluid was changed obviously in the treated group.Itsuggests that ischelium can serve as a effictive drug of preventing and treating high altitude is-chemic cerebrovascular disease.

关 键 词：高原 缺血性脑血管病 舒脑宁 

分 类 号：R594.3[医药卫生—内科学]