Stereochemical effects in mass spectrometry——Ⅺ.Negative ion fast atom bombardment mass spectrometry of saccharides and glycosides using phenylboronic acid as reagent  

作　　者：LI,Hong YANG,Hou-Jun CHEN,Shao-Nong CHEN,Yao-Zu Department of Chemistry,Lanzhou University,Lanzhou 730000 The author to whom correspondence should be addressed.Present address is Department of Chemistry,Tsinghua University,Beijing 100084 

出　　处：《Chinese Journal of Chemistry》1992年第4期337-343,共0页中国化学（英文版）

摘　　要：The negative ion fast atom bombardment (NIFAB) mass spectra of mono-,di-saccharides and glycosides using phenylboronic acid (PBA) as reagent have been studied.In the ion source,PBA reacts stereospecifically with the molecules containing cis-vicinal glycols to form characteristic ions, from which the stereo-isomers of saccharides can be definitely distinguished.Disaccharides and glyco- sides with β-glycosidic linkage seem to be unfavorabale to react with PBA,therefore,by comparison of the abundances of the characteristic ions,the configuration of the glycosidic linkage in these compounds may be inferred.The negative ion fast atom bombardment (NIFAB) mass spectra of mono-,di-saccharides and glycosides using phenylboronic acid (PBA) as reagent have been studied.In the ion source,PBA reacts stereospecifically with the molecules containing cis-vicinal glycols to form characteristic ions, from which the stereo-isomers of saccharides can be definitely distinguished.Disaccharides and glyco- sides with β-glycosidic linkage seem to be unfavorabale to react with PBA,therefore,by comparison of the abundances of the characteristic ions,the configuration of the glycosidic linkage in these compounds may be inferred.

关 键 词：FAB Stereochemical effects in mass spectrometry Negative ion fast atom bombardment mass spectrometry of saccharides and glycosides using phenylboronic acid as reagent acid 

分 类 号：O6[理学—化学]