SYNTHESIS OF DERIVATIVES OF 3-β-D-XYLOPYRANOSYL-1,2,4-OXADIAZOLES  

作　　者：Ling Jiao DONG Li LI Ling Tai MA Li He ZHANG School of Pharmaceutical Sciences,Beijing Medical University,Beijing 100083 

出　　处：《Chinese Chemical Letters》1992年第8期597-600,共4页中国化学快报（英文版）

摘　　要：The synthesis of derivatives of 3-β-D-xylopyranosyl-1,2,4-oxadiazoles is accomplished by condensing protected β-D-xylopyranosyl amidoxime with acid anhydrides or various substituted benzoyl chlorides in good yield.The structures of now derivatives were identified by spectra and elemental analysis. The stability of 1,2,4-oxadiazole ring and mechanism of cyclization were. investigated.The synthesis of derivatives of 3-β-D-xylopyranosyl-1,2,4-oxadiazoles is accomplished by condensing protected β-D-xylopyranosyl amidoxime with acid anhydrides or various substituted benzoyl chlorides in good yield.The structures of now derivatives were identified by spectra and elemental analysis. The stability of 1,2,4-oxadiazole ring and mechanism of cyclization were. investigated.

关 键 词：D-XYLOPYRANOSYL-1 2 4-OXADIAZOLES SYNTHESIS OF DERIVATIVES OF 3 台五 

分 类 号：O6[理学—化学]