银翘散解热机理的研究——Ⅱ、银翘散对体外培养单核细胞产生内生致热原的影响  

Effect on EP Production of MNC by Yinqiao San in Vitro

作　　者：杜力军[1] 沈映君[1] 国月英 马茹[2] 

机构地区：[1]成都中医学院,成都610075 [2]河南省新乡市中心医院检验科,新乡453001

出　　处：《中药药理与临床》1992年第1期8-10,共0页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：以伤寒副伤寒甲乙混合菌苗作为激活物观察了银翘散和氢化可的松对体外培养MNC合成释放EP的影响。结果表明银翘散对EP合成无明显影响,氢化可的松则可明显抑制之。提示银翘散的解热作用可能在于阻断EP产生以后的环节。By using typhoparatyphoid vaccine as an actor (50×106 germs/1 ×106 MNC), Ying-iao San, atypical antipyrettic recipe, as a manager (77.2mg/l ×106 MNC), cortison as another manager (1mg/1×106MNC), it was studied that EP production of MNC in vitro. It was showed that yinqiao San could not stop MNC producing EP in evidence,but cor-tison could do it. So, Yinqiao San would have the antipyretic effect in other fever links just after EP production.

关 键 词：银翘散 氢化可的松 内生致热原 

分 类 号：R28[医药卫生—中药学]