局部脑血流的单光子发射CT显像对难治性癫痫病灶的定位价值  

The Localizing Evaluation in Intractable Epilepsy with rCBF SPECT Image

作　　者：李沂[1] 胡平[1] 石锐[1] 曾世荃[1] 林增桃[1] 周列民 胡裕全[3] 林木田[3] 

机构地区：[1]中山医科大学附一院核医学科,邮政编码510080 [2]中山医科大学附一院,神经科邮政编码510080 [3]中山医科大学附三院神经外科

出　　处：《影像诊断与介入放射学》1992年第1期55-,92,共2页Diagnostic Imaging & Interventional Radiology

摘　　要：笔者应用局部脑血流(rCBF)的单光子发射 CT(SPECT)显像方法对34例临床确诊为难治性癫痫的患者进行了发作间期的检查。结果表明:34例患者均见到 rCBF 减少,其中30例呈局灶性改变,可作出定位诊断,癫痫病灶的检出率为88.24%(30/40),显著优于 CT、头皮电极 EEG 和蝶骨电极 EEG描记。17例复杂部分性发作的病灶多数位于颞叶或累及颞叶(13/17),但亦见于额叶。简单部分发作、复杂部分性发作或复杂部分性发作继发大发作的多数病灶局限,适宜于手术治疗。11例外科治疗后随访结果表明:切除 rCBF 显像所示之病灶的疗效最佳,仅作胼胝体切开的效果次之.rCBF 显像为制定手术方案提供了依据.rCBF SPECT imaging,CT and EEG were performed in 34 patients with medically intractable epilepsy during the interictal period.The result showed that there were focal rCBF decreases in 30 of 34 patients and the detecting rate of epileptic focus was 88. 24%.Compared with CT and scalp or sphenoid electrode EEG,rCBF SPECT showed more advantage for discovering the abnormalities in the epileptics.Among 17 patients with Com- plex Partial Seizure(CPS),rCBF SPECT showed that most of epileptic foci were localized at temporal lobes,while the others at frontal or parietal lobes.The result suggested that the pa- tients with Simple Partial Epilepsy(SPS),CPS and Secondarily Generalized Epilepsy of CPS(SecGE)were suitable for surgical treatment,because of their localizing epileptic foci.

关 键 词：癫痫 难治性 脑血流 SPECT显像 

分 类 号：R445[医药卫生—影像医学与核医学]