HIGH EXPRESSION OF HUMAN FACTOR IX cDNA DRIVEN BY HCMV PROMOTER IN MAMMALIAN CELLS  

作　　者：王平 戴一凡 邱信芳 薛京伦 

机构地区：[1]Institute of Genetics, Fudan University, Shanghai 200433, PRC [2]Institute of Genetics, Fudan University, Shanghai 200433, PRC Ⅰ. INTRODUCTION Clotting factor Ⅸis an essential member in the intrinsic clotting pathway, and the deficiency of factor Ⅸmay cause hemophilia B. An important subject on gene therapy for hemophilia B is to increase the protein products of factor Ⅸin human cells. In our earlier studies, we have constructed several recombinant retroviral vectors with factor Ⅸ

出　　处：《Chinese Science Bulletin》1992年第1期52-55,共4页

基　　金：This work was supported by a grant from National High Technology Program 863-102-17-40.

摘　　要：Ⅰ. INTRODUCTION Clotting factor Ⅸ is an essential member in the intrinsic clotting pathway, and the deficiency of factor Ⅸ may cause hemophilia B. An important subject on gene therapy for hemophilia B is to increase the protein products of factor Ⅸ in human cells. In our earlier studies, we have constructed several recombinant retroviral vectors with factor

关 键 词：CLOTTING FACTOR Ⅸ HCMV PROMOTER gene expression. 

分 类 号：N[自然科学总论]