仙人掌粉对大鼠高脂血症的预防作用  

Preventive effect of the dry powder of opuntia in rats with hyperlipemia

作　　者：刘浩[1] 李春艳[1] 崔美芝[1] 闫雅更[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院实验动物中心,黑龙江省哈尔滨市150001

出　　处：《中国临床康复》2004年第18期3550-3551,共2页Chinese Journal of Clinical Rehabilitation

基　　金：黑龙江省攻关课题资助项目(SYOZ-04)~~

摘　　要：目的:研究仙人掌粉对大鼠高脂血症的影响。方法:将Wistar大鼠分为4组:即正常饲料组(喂基础饲料)、正常饲料加仙人掌组(喂基础饲料加仙人掌粉)、高脂饲料组(喂高脂饲料)和高脂饲料加仙人掌组(喂高脂饲料加仙人掌粉),每组10只,喂养3周。于实验前后各采血1次测血清总胆固醇、高密度脂蛋白胆固醇(high-densitylipoproteincholesterol,HDL-C),并且计算低密度脂蛋白胆固醇(LDL-C)、动脉硬化指数(总胆固醇/HDL-C)。结果:正常饲料组血脂(mmol/L)及动脉硬化指数基本无改变(总胆固醇:1.64±0.30,总胆固醇/HDL-C:1.27±0.25);正常饲料加仙人掌总胆固醇降低(1.45±0.30);高脂饲料组血脂及动脉硬化指数明显升高(总胆固醇:11.93±2.71,总胆固醇/HDL-C:9.86±0.42);高脂饲料加仙人掌组血脂及动脉硬化指数比正常饲料组高,比高脂饲料组低(总胆固醇:4.13±1.42,总胆固醇/HDL-C:3.13±0.35);高脂饲料加仙人掌组与高脂饲料组比较差异有显著意义。结论:仙人掌粉能够阻止血脂升高,对高脂血症有预防作用。AIM:To study the effect of dry powder of opuntia on hyperlipemia of rats. METHODS:Forty Wistar rats were divided into four groups of 10 each:The normal control group(fed with basic feed,group A),group B(fed with basic feed and dry powder of opuntia),group C(fed with high fat feed),group D(fed with high fat feed and dry powder of opuntia),and all rats were fed for 3 weeks.Before and 3 months after experiment,samples of blood were taken for determination of levels of total cholesterol(TC),triglyceride(TG) and high density lipoprotein cholesterol(HDL C),besides,low density lipoprotein cholesterol(LDL C) and index of arteriosclerosis(TC/HDL C) were calculated. RESULTS:There was no change in TC level[(1.64±0.30) mmol/L] and TC/HDL C(1.27±0.25) in group A;TC level was decreased in group B(1.45±0.30);TC level[(11.93±2.71) mmol/L] and TC/HDL C(9.86±0.42) in group C were increased obviously; while TC level[(4.13±1.42)mmol/L] and TC/HDL C(3.13±0.35) in group D was higher than those in group A but lower than those in group C,and there was a significant difference between group C and D. CONCLUSION:The dry powder of opuntia may protect the rats from hyperlipemia.

关 键 词：仙人掌 高脂蛋白血症 大鼠 WISTAR 

分 类 号：R589.2[医药卫生—内分泌]