慢性活动型肝炎肝硬化医院内感染隐球菌脑膜炎三例报告  

Report on the 3 Cases of Chronic Active Hepatitis Cirrhosis and Cryptococcal Meningitis of Nosocomial Infection

作　　者：孙洪清[1] 骆成榆[1] 

机构地区：[1]上海市传染病医院

出　　处：《中华医院感染学杂志》1992年第2期92-95,共4页Chinese Journal of Nosocomiology

摘　　要：本文报道我院收治的慢性活动型肝炎肝硬化医院内感染隐球菌脑膜炎三例,其中男性1例,女性2例,年龄分别为44、42、35岁。均有慢性活动型肝炎的临床表现及肝脾肿大、蜘蛛痣、肝掌和腹水等肝硬化体征。分别于住院12月、5月、2月后出现发热和头痛等症状。经腰穿脑脊液隐球菌涂片和培养阳性,确诊为医院内感染隐球菌脑膜炎。本文重点对医院内真菌感染的易感因素、发病机理,临床特征,早期诊断和预防措施作了讨论。In the article we give a report on the treatment of 3 cases of chronic active hepatitis (CAH), cirrhosis and crypto coccol meningitis of nosocomial infection by our hospital. One of the patients was a man and the other two were women and their ages were 44, 42 and 35 respectively. All of them had clin- ical manifestations of CAH and stigmas of cirrhosis such as hepatosplenomegaly, spider, liver palm and ascites. They had symptoms of fever, headache accompanied by other things after staying in the hospoital for 12, 5 and 2 months respectively. By means of cryptococci of cerebrospinal fluid through smear and culture by lumber puncture, they were finally dignosed as cryptococcal menigitis of nosocomial infection. The article puts emphasis on the discussion about predispose facter of nosocomial fungous in- fection, pathogenetic mechanism, clinical character, early diagnosis and preventive measures.

关 键 词：慢性活动型肝炎 肝硬化 医院内感染 隐球菌脑膜炎 

分 类 号：R197[医药卫生—卫生事业管理]