高红症患者由高海拔进入平原后血液流变学的改变对肺循环及微循环灌注的影响(附9例高原红细胞增多症分析)  

EFFECTS ON DEACCLIMATIC MICROCIRCULATION PERFUSION OF CYTORHELOGY OF PATIENTS WITH HIGHLAND ERYTHROCYTOSIS

作　　者：韩锦玲 张秀梅 陈虹[1] 于杰 杨之[2] 顾浩平[2] 刘金荣[2] 恽寿全[2] 潘卫红[2] 刘峰[2] 范秀茹[2] 

机构地区：[1]青海省儿童医院 [2]青海省人民医院

出　　处：《高原医学杂志》1992年第1期39-42,共4页Journal of High Altitude Medicine

摘　　要：本文观察高原红细胞增多症男性患者9名,脱离3760m高原环境后,分别到达西宁市2261m,苏州市15m两上地区实地进行微循环、血液流变学、血气、肺动脉压力等测定。结果:1.随海拔高度下降,球结膜、甲襞微循环指标明显改善,具有高度显著差异(p<0.01);2.全血比粘度(ηb)、血沉(ESR)、红细胞压积(HCT)、血沉方程K值、纤维蛋白原、红细胞电泳(EPT)等相应改善,均有高度显著差异;3.血红蛋白(Hb)肺动脉平均压(PAP)、全肺阻力(TPR)随海拔高度下降而降低,心排指数(CL)增加,具有高度显著差异。We observad the measuremants of micorcirculation cytorhelogy.Hb,pulmonary resistance pressure (PAP).Total pulmonary resistanee(TPR)and Cardiac Indes(CI)of 9 male patients of highland erythrocytosis, when they had left the high altitude(3760M)arrived to Xining(2261M)and Suchou(15M)successively. The Results Showed:1.With descending of the heihgt,the indices of micorcirculatic measurements changed obviously.The weighted integraging value of the status of cannal,flowing and margin Of bulbar conjunetuva micoreireulation reduced from 24.84±8.89 to 12.08±3.30.The Weighted integrating value of nail folds micocirculation reduce from 12.86±3.30 to 8.534±1.52.All results showed the significant difference(P<0.01).2.When the patients left high altitude and arrived plain,many items of eytorheology improved evidently,Hb reduced from 9.327±0.319 to 7.08±0.46,ESR increased from 0.111±0.333mm/h to 5.111±5.84 mm/h.HCT from 71.333±9.447 to 62.555±7.748(v％),the K value of ESR equation from 0.712±2.137 to 39.334±36.163.fibrinogenfrom 165.666±82.611(mg％)to 268.333±59.622(mg％)and EPT from 20.853±1.483 to 16.960±0.870(s).3.The values of Hb, PAP and TPR were reduce by the lower of the height,but CI raised.

关 键 词：高原红细胞增多症 脱适应红细胞流变与微循环灌注 

分 类 号：R8[医药卫生—临床医学]