心肝宝治疗晚期血吸虫病肝纤维化的临床研究  

OBSERVATIONS ON XINGANBAO THERAPY OF LIVER FIBROSIS CAUSED BY ADVANCED SCHISTOSOMIASIS

作　　者：钱燕喃 周明华[1] 尚国光[1] 魏宝茹 华海涌[1] 王德威 刘铭堂 贺国铭 刘伯荧 赵伯阳 

机构地区：[1]江苏省血吸虫病防治研究所 [2]昆山市血防站 [3]泰兴县卫生防疫站 [4]武进县卫生防疫站 [5]江苏省血防办公室

出　　处：《中国血吸虫病防治杂志》1991年第5期267-270,共4页Chinese Journal of Schistosomiasis Control

摘　　要：用心肝宝胶囊治疗晚期血吸虫病肝纤维化病人106例。男性58例(54.72％),女性48例(45.28％)。每例均有门静脉高压的诊断依据。每d剂量为2.25g(250mg/粒),分3次口服,连续2个月。结果能使患者症状减轻或消除,肝功能好转,血清白蛋白上升,Y球蛋白下降;免疫功能得到调整;门、脾静脉内径缩小。显效者15例(14.15％),有效80例(75.47％),总有效率为89.62％。106 patients with liver fibrosis, 58 men (54.72%) and 48 women (45.28%), were treated with Xinganbao. All of these cases were diagnosed as portal hypertension of advanced schistosomiasis. The drug was given in a daily dose of 2.25g (250mg/capsule) 3 times a day for a succession of 2 months. The result of our study suggests that Xinganbao therapy can relieve and/or eliminate the clinical symptoms of advanced schistosomiasis with liver function recovered, serum albumin raised, γ-globulin decreased, immune function adjusted and caliber of portal and spleen vein much diminished. The total rate of efficacy was 89.62%, of which, 14.15% (15 cases) markedly improved while 75.47% (80 cases) moderately.

关 键 词：晚期血吸虫病 肝纤维化 脾静脉内径 门静脉高压 肝宝 血清白蛋白 食道静脉曲张 免疫功能 纤维化指标 心肝宝胶囊 

分 类 号：R532.21[医药卫生—内科学]