A simple and effective method for fluoroalkylation——the addition of fluoroalkyl iodide to olefins in the presence of hydrogen peroxide  

作　　者：CHEN,Qing-Yun CHEN,Ming-Fang Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032 

出　　处：《Chinese Journal of Chemistry》1991年第2期184-188,共0页中国化学（英文版）

基　　金：This project was supported by the National Natural Science Foundation of China.

摘　　要：Addition of fluoroalkyl iodides to olefins in the presence of hydrogen peroxide(H_2O_(?)) in acetone,acetonitrile or ethanol gave the corresponding 1:1 adducts in good yields.Reaction of fluoroalkyl iodide with diallyl ether(DAE)yielded tetrahydrofuran derivatives,p-Hydroquinone (p-HQ)can partly suppress the reaction.A radical initiation mechanism is proposed.Addition of fluoroalkyl iodides to olefins in the presence of hydrogen peroxide(H_2O_(?)) in acetone,acetonitrile or ethanol gave the corresponding 1:1 adducts in good yields.Reaction of fluoroalkyl iodide with diallyl ether(DAE)yielded tetrahydrofuran derivatives,p-Hydroquinone (p-HQ)can partly suppress the reaction.A radical initiation mechanism is proposed.

关 键 词：A simple and effective method for fluoroalkylation the addition of fluoroalkyl iodide to olefins in the presence of hydrogen peroxide 

分 类 号：O6[理学—化学]