高原性红细胞增生与红细胞增多症  

HIGH ALTITUDE ERYTHROCYTOSIS AND POLYCYTHEMIA

作　　者：王占刚[1] 崔芝忠 张旭辉[1] 

机构地区：[1]青海省高原医学科学研究所

出　　处：《高原医学杂志》1991年第2期9-12,共4页Journal of High Altitude Medicine

摘　　要：作者赴海拔5000米高原对Hb(血红蛋白)、Hct(血球压积)等反映红细胞变化的指标进行了较长时间的观察。结果发现在进入高原后Hb和Hct即见持续增高,于第8周时上升到高峰,此后二者处于稳定状态。红细胞增生的速率及程度与受检者原居住地的海援高度和年龄有关,同时也存在着明显的个体差异。第8周时,有5例(占25％)达到高原红细胞增多症的血液学标准,其中有3例出现了高原红细增多症的症状和体征。并就此进行了讨论。Twenty health men's Hb and Hct had been observing continuously in field. They had worked at 5 000m high altitude for. three months. The results were that Hb and Hct reached peak at eighth week from begining, and then kept steady state in high level. The rising rates of Hb and Hct in lowland group were higher than Xin- ing (2 260m) group (p<0.05). The Hb and Hct of lowland group were higher both before and after reaching steady state (p<0.05). The rising rate of Hb and Hct were higher in the subjects above forty yrs than in that below forth yrs (p<0.05). There was no significant diffrence between two groups at steady state (p<0.2). Therefor we recognized that the rising rate of red blood cells at high altitude is not only related with elevation but also ralated hypoxia degree and age. At eighth week the Hb and Hct in five cases met the standard of high altitude polycythemia (Hb>200g/L; Hct>65%),three of them showed symtoms and clinical signs of high alitutude polycythemia. There was a per- sonal differnt greatly in rising rate of the red blood cells and developing cause from physiologic high altitude ery- throcytosis to pathologic polycythemia. Besides height of altitude and degree of hypoxia there was a clear relati- noship with personal sensitivity. It is concluded that the diagnosis of the high alitutde polycythemia not only de- pends on standard of haematology but also considers clinical pathological sigbs.

关 键 词：高原 红细胞增生 高原红细胞增多症 

分 类 号：R8[医药卫生—临床医学]