补阳还五汤配合羟基脲治疗原发性血小板增多症的效果评估（英文）  

Efficacy evaluation of Buyang Huanwu Decoction and Hydroxyurea in treatment with essential thrombocytosis

作　　者：康财庸[1] 荣光[1] 孟庆刚[1] 

机构地区：[1]北京中医药大学基础医学院,北京100029

出　　处：《中国生化药物杂志》2014年第2期101-103,共3页Chinese Journal of Biochemical Pharmaceutics

基　　金：北京中医药大学创新团队项目(2011CXTD03);十二五科技支撑计划项目(2013BAI102B10)

摘　　要：目的评估补阳还五汤配合羟基脲治疗原发性血小板增多症的临床效果。方法将120例原发性血小板增多症患者随机均分为2组。观察组60例采用补阳还五配汤合羟基脲治疗;对照组60例采用羟基脲治疗。6个月后评估治疗效果。结果治疗后,观察组疗效好于对照组,差异有统计学意义(P<0.05);观察组中医证候缓解程度优于对照组,差异有统计学意义(P<0.05)。2组治疗后血小板计数、巨核细胞计数均有所下降;与对照组比较,观察组患者治疗后血小板计数、巨核细胞计数下降更为明显,差异均具有统计学意义(P<0.05)。结论中西医结合治疗在治疗原发性血小板增多症方面优于单纯西医疗法。Objective To observe the effectiveness of treating essential thrombocytosis(ET) with Buyang Huanwu Decoction plus hydroxyurea. Methods 120 patients with ET were randomly divided into observation group(OG) and control group(CG). Patients from OG were treated with Buyang huanwu decoction plus hydroxyurea, while those from CG were given hydroxyurea. After 6 months, the treatment effectiveness indexes including symptoms in a sense of chinese medicine, cell counts and saffy were observed. Results Total effective rate of OG was higher than that of CG(P<0.05). TCM symptoms remission in OG group was better than that of CG(P<0.05). After treatment, blood platelet count and megakaryocyte count were decreased in two groups(P<0.05), and the difference between two groups was signiifcan(P<0.05). Conclusion The therapy combined Chinese and western medicine deals with ET is better than simple western medicine treatment.

关 键 词：羟基脲 补阳还五汤 原发性血小板增多症 中西医结合疗法 

分 类 号：R259[医药卫生—中西医结合]