泌尿系感染与肾结石复发的临床探讨  

Clinic Study of the Relationship between Urinary Tract Infection and Recurrent Kidney Stone

作　　者：薛爱兵 金讯波[1] 张海洋[1] 许丽娜[1] 张栋[1] 

机构地区：[1]山东大学附属省立医院泌尿微创中心,山东济南250014

出　　处：《泌尿外科杂志（电子版）》2014年第2期15-20,共6页Journal of Urology for Clinicians(Electronic Version)

摘　　要：目的探讨泌尿系感染与肾结石的关系及抗感染治疗对预后的影响。方法回顾性分析38例自2011年11月至2013年3月间在本中心行手术治疗的肾结石患者的临床资料,患者均为原发性单侧肾结石或单侧肾结石合并输尿管结石,手术方式为PCNL或者PCNL、URL相结合,术前所有尿常规WBC升高病人均行经验性抗感染治疗,尿培养结果阳性者则根据药敏结果行抗感染治疗,疗程为3～16天;术后所有病人均应用抗生素抗感染治疗3～15天,术后随访时间为12～29个月。文章主要分析患者是否合并感染症状、尿常规及尿培养结果、术前抗感染治疗时间、术后抗感染治疗情况,并跟踪随访其院外是否存在泌尿系感染及结石复发。结果术后跟踪随访时间为12～29个月,复发者5例,其中尿常规阴性出院者共30人,复发1例;尿常规WBC升高者8例,出院后均未用抗生素规范治疗,4例复发。结论患者复发率与泌尿系炎症控制情况具有相关性;合理应用抗生素控制尿路感染对于预防泌尿系结石复发具有一定效果。Objective There has been proved to be a close relationship between urinary stone disease and u-rinary tract infection,and we try to clarify this relationship and get a better understanding of how anti-infection therapy can affect the prognosis of kidney stone. Methods Review of 38 patients from November 2011 to March 2013 from Minimally Invasive Urology Center of Shandong Provincial Hospital. The patients we choose all have unilateral kidney stones or accompanied with ureter stone disease and had successful surgeries. All patients had anti-infection therapy time 3~16 days in the pre-operation and had anti-infection therapy 3~15 days in the post-operation until clinical symptoms were removed. They had been followed-up for 12~29 months. Results After 12~29 months'follow-up study,5 patients had a relapse. Of the 30 patients with negative urinalysis or rational anti-infection therapy,1 patients had a recurrence kidney stone. Of the 8 patients with positive results or without rational anti-infection therapy there are 4 patients had a relapse. Conclusions Anti-infection thera-py could be used in preventing the recurrence of non-infection stone disease as well as infection stones.

关 键 词：泌尿系结石 感染 抗炎治疗 复发 预防 

分 类 号：R692.4[医药卫生—泌尿科学] R691.3[医药卫生—外科学]