糖基化终末产物及其受体与糖尿病视网膜病变的研究进展  

Research progress on advanced glycation end products and its receptor in diabetic retinopathy

作　　者：田敏[1] 李友谊[1] 吕红彬[1] 

机构地区：[1]泸州医学院附属医院眼科,四川省泸州市646000

出　　处：《眼科新进展》2013年第12期1194-1197,共4页Recent Advances in Ophthalmology

基　　金：四川省教育厅基金资助(编号:11ZA244)~~

摘　　要：糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病常见且严重的微血管并发症之一,严重影响患者的健康和生活质量。DR的发生与多种因素相关,其发病机制至今尚未完全阐明,越来越多的研究表明,糖基化终末产物及其受体在DR的发生和发展中起着重要作用。本文就有关糖基化终末产物及其受体在DR中的作用机制作一综述。Diabetic retinopathy(DR)is one of the most common and serious complications of diabetes mellitus which affects the health and quality of life seriously.The occurrence of DR is related to a variety of factors,the clear and detailed pathogenesis of DR is not elucidated.More and more evidences show that advanced glycation end products and its receptor play an important role in DR.This article reviews the advanced glycation end products and its receptor in the mechanism of DR.

关 键 词：糖尿病视网膜病变 糖基化终末产物 受体 

分 类 号：R587.2[医药卫生—内分泌]