老年心血管疾病患者睡眠呼吸暂停低通气综合征的患病调查  

Prevalence of obstructive sleep apnea hypopnea syndrome in the aged patients with cardiovascular disease

作　　者：侯晓平[1] 马艳敏[1] 缪京莉[1] 张婧[1] 陈艳芳[1] 王玉军[1] 

机构地区：[1]解放军空军总医院干部病房,北京100142

出　　处：《中国临床保健杂志》2013年第6期561-565,共5页Chinese Journal of Clinical Healthcare

摘　　要：目的调查老年心血管病患者睡眠呼吸暂停低通气综合征(SAHS)的患病情况。方法采用微动敏感床垫睡眠监测系统对60岁以上住院老年心血管病患者进行睡眠呼吸监测并数据分析。结果 127例患者(男性101例,女性26例),平均(76.4±6.8)岁,分别或合并患有冠心病、高血压、各种心律失常以及糖尿病及空腹血糖受损和(或)糖耐量异常、高尿酸血症、慢性肾脏病等。检出SAHS 107例,患病率84.3%。SAHS组冠心病患病多于对照组,P<0.05;SAHS患者平均呼吸紊乱指数(AHI)22.6±14.7,其中AHI≥15者64例,呼吸事件主要为阻塞性,但随着增龄,阻塞性呼吸事件时长减少,低通气事件时长增加。监测血氧饱和度118例均存在夜间低氧血症,重度患者50例占41.7%,最低血氧饱和度(LO2)(79.0±7.2)%,平均血氧饱和度(AO2)(92.8±2.7)%。患者年龄与低通气指数正相关,与LO2负相关,均P<0.01,在调整呼吸紊乱参数后,年龄与LO2的负相关依然存在,r=-0.223,P<0.05。结论老年心血管病患者有很高的SAHS和夜间低氧血症患病率,SAHS的低通气事件加重老年患者随增龄增加的夜间低氧血症。Objective To investigate the prevalence of obstructive sleep apnea hypopnea syndrome (OS-AHS)in the aged patients with cardiovascular disease.Methods The sleep and breath monitoring was performed by using micro -movement sensitive mattress sleep monitoring system (MSMSMS)in 127 hospitalized patients with car-diovascular disease aged more than 60 years old or over at least two nighs for detecting SAHS.Results A total of 127 patients (101 males and 26 females)were included in the study.The average age of patients was (76.4 ±6.8) years.The patients were alone or complicated with coronary heart disease,hypertension,arrhythmias,heart failure,or/and diabetes and impaired fasting glucose and (or)glucose tolerance abnormalities,hyperuricemia and chronic kidney disease.There were totally 107 cases with OSAHS (84.3%).The number of cases with coronary heart disease in SAHS group was more than that in the control group.The mean apnea hypopnea index (AHI)was (22.6 ±14.7), of which 64 cases were AHI≥15.The majority were obstructiverespiratory events.However,with the increase in the age,the decreased length of obstructive respiratory events and increased length of hypopnea events were observed. Nocturnal hypoxemia was detected in all of 118 cases who received monitoring of oxygen saturation,of which 50 cases (41.7%)were severe.The average level of lowest oxygen saturation(LO2 )was (79.0 ±7.2)% and mean oxygen saturation(AO2 )was (92.8 ±2.7)%.The age of patients was significantly positively correlated with HI and nega-tively correlated with LO2 (P <0.01).The negative correlation between age and LO2 was still present after the adjust-ment of the parameters of breathing disorder(r =-0.223,P <0.05).Conclusions The prevalence of OSAHS and nocturnal hypoxemia disease is high in the aged patients with cardiovascular diseases.The hypopnea events of OSAHS aggravate the nocturnal hypoxemia,which is increased with age in the aged patients.

关 键 词：睡眠呼吸暂停综合征 心血管疾病/并发症 患病率 老年人 

分 类 号：R54[医药卫生—心血管疾病]