部队官兵肺炎衣原体感染与强直性脊柱炎关系的调查研究  

The relationship between Chlamydia pneumoniae infection and ankylosing in military conscripts

作　　者：曾华[1] 林桂英[2] 冯修高[2] 陈频[2] 林忆阳[2] 徐向进[2] 

机构地区：[1]南京军区福州总医院感染控制科,福建福州350025 [2]南京军区福州总医院内分泌科,福建福州350025

出　　处：《东南国防医药》2013年第2期110-112,共3页Military Medical Journal of Southeast China

基　　金：福建省自然科学基金(2011J1234);全军医药卫生科研基金(06MA113)

摘　　要：目的探讨部队官兵肺炎衣原体(Chlamydia pneumoniae,Cp)感染与强直性脊柱炎(ankylosing spondylitis,AS)之间的关系。方法收集门诊就诊的军人AS患者,记录临床资料,测定血液中肺炎衣原体抗体,设置健康军人和健康非军人作为对照。结果健康军人和健康非军人近期肺炎衣原体感染均有较高的发生率,两者之间没有显著性差异,但健康军人CpIgM阳性率高于健康非军人(P<0.01)。在AS患者,近期肺炎衣原体感染率明显高于健康者(P<0.01),且Cp IgM与AS的疾病活动有关。结论 AS军人患者易发生肺炎衣原体感染,且肺炎衣原体感染与AS的疾病活动有关。Objective Investigation of relationship between Chlamydia pneumoniae infection and ankylosing among military conscripts.Methods Forty six AS servicemen,44 healthy servicemen and 41 healthy residents were enrolled into this study.Serum anti-Cp antibodies(Cp Ig)were tested using the enzyme-inked immunosorbent assay(ELISA).Clinical and experimental data were collected.Patients with positive CplgM or CplgA were considered as having a recent Cp infection.χ2 test and T test were used for statistical analysis.Results Both healthy servicemen and healthy residents had a high prevalence for Cp IgA or Cp IgM antibody,but healthy servicemen had higher prevalence for Cp IgM antibody(P<0.01).In AS servicemen,recent Chlamydia pneumoniae infection occurred more frequently than that in healthy servicemen(P<0.01),and CplgM was associated with disease activity in AS patients.Conclusion AS servicemen are susceptible to Chlamydia pneumoniae infection and the disease activity are associated with CplgM antibody.

关 键 词：强直性脊柱炎 肺炎衣原体 感染 军人 

分 类 号：R593.23[医药卫生—内科学]