临床活体小肠移植国内外研究进展  

Advances inliving-related small intestinal transplantation

作　　者：吴国生[1] 

机构地区：[1]西安第四军医大学西京消化病医院,710032

出　　处：《中华结直肠疾病电子杂志》2013年第5期221-223,共3页Chinese Journal of Colorectal Diseases(Electronic Edition)

摘　　要：过去30年小肠移植取得了显著进展,现在小肠移植不再是一项被认为成实验性的技术,而是治疗不可逆性肠衰竭的可行治疗选择。根据小肠移植注册委员会近年公布的资料,全球小肠移植患者的总体1年和5年生存率已分别超过70%和50%,但排斥反应和感染仍是术后常见的严重并发症。我们简要概括了活体小肠移植领域的最新进展,包括手术的适应症、受体如何评价、如何控制手术后的排斥反应和感染等。Great progress has been achieved in of small bowel transplantation over the past 30 years. Currently,SBT is no longer considered an experimental procedure and has become one of a lifesaving therapy in selective patients with irreversible loss of intestinal function.The Transplant Registry has shown that current 1-yr and 5-yr patient and graft survival rates are more than 70%and 50%respectively.Postoperative infection and rejection are still the most disturbing complications in patients undergoing small bowel transplantation.This article summarizes recent advances in its indications, the evaluation of candidates, controlling rejection and infection for living-related small bowel transplantation after surgery.

关 键 词：器官移植 外科手术 免疫耐受 移植物排斥 感染 

分 类 号：R656.7[医药卫生—外科学]