血糖浓度影响肝脏及胰腺FDG摄取的研究  

Effects of blood glucose level on FDG uptake by liver and pancreas in ^(18)F-FDG PET/CT

作　　者：张建[1] 程超[1] 左长京[1] 王少雁[1] 崔斌[1] 孔令山[1] 

机构地区：[1]第二军医大学长海医院核医学科,上海200433

出　　处：《功能与分子医学影像学（电子版）》2012年第2期137-139,共3页Functional and Molecular Medical Imaging(Electronic Edition)

摘　　要：目的研究在18F-FDGPET/CT检查中血糖浓度对肝脏摄取FDG的影响。方法分析30例行18F-FDGPET/CT全身扫描的健康体检者肝脏和胰腺的最大标准摄取值(SUVmax)与血糖浓度、年龄、肝脏和胰腺的CT值之间的关系。结果肝脏的SUVmax与血糖浓度具有明显相关性(r=0.61,P<0.05),肝脏SUVmax与年龄及肝脏CT值无显著相关性(P>0.05),胰腺SUVmax与血糖浓度、胰腺CT值及患者年龄无显著相关性(P>0.05)。结论血糖浓度是肝脏SUV的重要影响因素,血糖浓度升高,肝脏SUV随之增大。因此,行18F-FDGPET/CT检查前应将血糖控制在合理范围内,图像判读时应充分考虑血糖浓度对肝脏FDG摄取的影响。Objective To explore the effects of blood glucose level on FDG uptake by liver in 18F-FDG PET/CT.Methods 18F-FDG PET/CT studies of 30 patients were analyzed for standardized uptake value(SUV),blood glucose level,age,the liver and pancreas CT value.Results Correlation between liver SUVmax and blood glucose level is significant(r = 0.61,P < 0.05),Correlation between liver SUVmax and age,and the liver CT value is not significant(P > 0.05).Correlation between pancreas SUVmax and blood glucose level,age and the pancreas CT value is not significant(P > 0.05).Conclusion The blood sugar concentration is an important impact factor of liver SUV.Blood glucose level heats up,and liver SUV immediately increases.Therefore,before the 18F-FDG PET/CT scanning blood glucose level should be controled within the reasonable scope.We must take the effects of blood glucose level on FDG uptake by liver into consideration,while judging the imaging.

关 键 词：氟脱氧葡萄糖 体层摄影术 发射型计算机 体层摄影术 X线计算机 标准摄取值 血糖浓度 

分 类 号：R446.1[医药卫生—诊断学]