BC_1和F_2设计下利用单标记信息检测QTL的效率  

Efficiencies of QTL Detection under BC_1 and F_2 Design by Using Single Marker Information

作　　者：吴道斌[1] 李明丽[1] 鲁立刚 鲁绍雄[1] 

机构地区：[1]云南农业大学动物科技学院,云南昆明650201 [2]毕节地区畜牧兽医科学研究所,贵州毕节551700

出　　处：《云南农业大学学报》2011年第5期621-624,共4页Journal of Yunnan Agricultural University

基　　金：国家"863"计划重点项目(2008AA101001);云南省自然科学基金项目(2003C0047M)

摘　　要：本文采用计算机模拟方法研究了BC1和F2设计不同资源群体规模、性状遗传力、QTL效应(QTL方差占加性遗传方差的比例)和标记-QTL间图距下单标记分析对QTL的检测效率。结果表明:当资源群体的规模较大,目标性状的遗传力较高,QTL效应较大,所检测的标记距离QTL的距离较近时,无论是BC1设计还是F2设计,都可获得较高的QTL检测效率。但在其他条件相同时,F2设计对QTL的检出率明显高于BC1设计。In this paper,an experiment of quantitative trait loci(QTL) detection in BC1 and F2 designs was simulated by computer.The QTL detection efficiencies under different sizes of resource population,trait heritabilities,QTL effect(the ratio of QTL variance to additive genetic variance) and marker-QTL map distances were analyzed.The results showed that the detecting power of QTL was higher in BC1 and F2 design in the following situations: larger size of resource population,higher heritability of target trait,larger QTL effect and shorter distance between the detected marker and QTL.However,the QTL detected ratios of F2 design were obviously higher than those of BC1 design under the same condition.

关 键 词：QTL检测 BC1设计 F2设计 单标记分析 检测效率 

分 类 号：S813[农业科学—畜牧学]