药用园林植物紫萼的化学成分  

Chemical Constituents of Hosta ventricosa,an Ornamental Medicinal Plant

作　　者：杨世仙[1,2] 赵富伟[1] 王欢[1,3] 黄巧琴[1,2] 徐金金[1,3] 王跃虎[1] 龙春林[1,4] 

机构地区：[1]中国科学院昆明植物研究所资源植物与生物技术重点实验室,云南昆明650201 [2]云南农业大学园林园艺学院,云南昆明650201 [3]云南农业大学农学与生物技术学院,云南昆明650201 [4]中央民族大学生命与环境科学学院,北京100081

出　　处：《云南农业大学学报》2011年第5期662-667,共6页Journal of Yunnan Agricultural University

基　　金：国家自然科学基金项目(20972166;31070288)

摘　　要：百合科玉簪属的紫萼(Hosta ventricosa)常应用于园林造景、美化绿地,也是常用的室内观赏植物。作为一种药用植物,紫萼主要用于治疗吐血、崩漏、湿热带下、咽喉肿痛、胃痛、牙痛等。为全面了解和综合利用紫萼资源,笔者对其全草的化学成分进行了研究。运用D101大孔树脂、Sephadex LH-20和硅胶等柱层析及半制备HPLC等分离手段,对其化学成分进行了分离纯化,根据波谱数据对其结构进行了鉴定。从紫萼70%甲醇提取物中分离得到6个化合物,分别鉴定为α-羟基香荚兰乙酮(1),7-羟基香豆素(2),反式对羟基桂皮酸(3),(25R)-2α,3β-二羟基-5α-螺甾-9(11)-烯-12-酮(4),(25R)-2α,3β-二羟基-5α-螺甾-9(11)-烯-12-酮3-O-{O-β-D-吡喃葡萄糖基-(1→2)-O-[β-D-吡喃木糖基-(1→3)]-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷}(5)和(25R)-3β-羟基-5α-螺甾-9(11)-烯-12-酮3-O-{O-β-D-吡喃葡萄糖基-(1→2)-O-[β-D-吡喃木糖基-(1→3)]-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷}(6)。这些化合物均为首次从该种植物中分离得到。Hosta ventricosa(Liliaceae) is an ornamental plant used both outdoor and indoor.As a medicinal plant,it is used to treat hematemesis,metrorrhagia and metrostaxis,exceptional leucorrhea,sore throat,stomachache,toothache and so on.Hosta plants mainly contain steroid saponins,flavonoids and alkaloids.To understand and use H.ventricosa integratively,its chemical constituents were investigated by D101 macroporous resin,Sephadex LH-20,and silica gel column chromatography,and semi-preparative HPLC.The isolated compounds were identified by spectroscopic data.Six compounds,namely α-hydroxyacetovanillone(1),7-hydroxycoumarin(2),trans-p-hydroxycinnamic acid(3),(25R)-2α,3β-dihydroxy-5α-spirost-9(11)-en-12-one(4),(25R)-2α,3β-dihydroxy-5α-spirost-9(11)-en-12-one 3-O-{O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopryranoside}(5),and(25R)-3β-hydroxy-5α-spirost-9(11)-en-12-one 3-O-{O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopryranoside}(6),were isolated and identified from 70% methanol extracts of the plant.All of the compounds were found from this plant for the first time.

关 键 词：百合科 玉簪属 观赏植物 紫萼 甾体 

分 类 号：S682.19[农业科学—观赏园艺]