胱抑素C在类风湿患者心脏损害中的临床应用  

Clinical application of Cys C in the cardiac damage of patients with rheumatoid

作　　者：刘淑卓[1] 王建国[1] 王淑仙[1] 丑广程[1] 李伟[1] 朱姗姗[1] 苏维[1] 

机构地区：[1]河北大学附属医院,071000

出　　处：《环球中医药》2013年第S2期136-137,共2页Global Traditional Chinese Medicine

摘　　要：目的探讨Cys C检测在类风湿患者合并心脏损害中的应用价值,为预测RA合并心脏损害及其诊治提供参考依据。方法收集2010年~2013年间类风湿关节炎患者89例患者的血清,按有无心脏损害分为两组。结果 RA有心脏损害的发病率为37.1%,其血清Cys C水平明显高于其它两组血清水平,经统计学分析,其差异具有统计学意义(P【0.05);而RA无心脏损害组和健康对照组比较,经统计学分析,其差异无统计学意义(P】0.05)。结论检测RA患者血清Cys C水平,在预测心脏损害方面具有重要价值,为临床诊治提供重要参考,值得在临床推广应用。Objective To study the application value of Cys C in the cardiac damage of patients with rheumatoid and to provide a reference basis for the prediction of diagnosis and treatment of RA with cardiac damage .Methods Collected the serum of 89 patients of rheumatoid arthritis between 2010 and 2013 ,and detected the level of Cys C in serum with machine .They were divided into two groups ,one group was patients of cardi-ac damage with rheumatoid and the other group was no cardiac damage .Results The incidence of RA with cardiac damage was 37.1% .The level of Cys C in cardiac damage is significantly higher than the other two groups ,There was significant differences in comparison between the group of cardiac damage and the other two groups to the concentration of Cys C (P<0.05);There was no significant differences in comparison between the group of no cardiac damage with rheumatoid and the healthy groups to the concentration of Cys C (P>0.05) .Conclusion There was important val-ue in predicting cardiac damage to detect the level of Cys C in patients of rheumatoid ,which deserves further clinical application .

关 键 词：胱抑素C 类风湿性关节炎 心脏损害 

分 类 号：R541.2[医药卫生—心血管疾病]