应用静脉免疫球蛋白联合抗生素治疗重症获得性肺炎的临床疗效观察  

Clinical observation of pneumonia in 50 cases received intravenous immune globulin combined with antibiotics in the treatment of severe community

作　　者：陈德[1] 

机构地区：[1]四川省宜宾市第一人民医院,四川宜宾644000

出　　处：《当代医药论丛》2014年第1期23-24,共2页

摘　　要：目的：探讨分析应用静脉免疫球蛋白联合抗生素治疗重症获得性肺炎的临床疗效。方法：选取2010年9月～2013年9月间我院收治的重症获得性肺炎患者100例作为研究对象，将其随机分为对照组（50例）和实验组（50例），单纯使用抗生素（左氧氟沙星）为对照组患者进行治疗，应用静脉免疫球蛋白联合抗生素为实验组患者进行治疗，观察对比两组患者的临床疗效，并将对比的结果及两组患者的临床资料进行回顾性的分析。结果：经过一段时间的治疗，实验组患者治疗的总有效率为98.00%，对照组患者治疗的总有效率为86.00%，实验组患者治疗的总有效率明显优于对照组患者，差异显著（P＜0.05），具有统计学意义。实验组患者病灶的吸收率为52.00%，对照组患者病灶的吸收率为38.00%，实验组患者的病灶吸收率明显优于对照组患者，差异显著（P＜0.05），具有统计学意义。结论：应用静脉免疫球蛋白联合抗生素治疗重症获得性肺炎的临床疗效显著，值得在临床上推广应用。Objective:to analyze the efficacy and safety of intravenous immune globulin combined with antibiotics in the treatment of severe community acquired pneumonia,to shorten the treatment time,improve the therapeutic effect.Methods:randomly selected in 2010 September ~2013year in September severe community acquired pneumonia patients 100 patients as the research object,randomly divided into two groups.The control group of 50 cases,treated with antibiotics(levofloxacin) treatment; 50 cases of experimental group patients,treatment with intravenous immunoglobulin combined with antibiotics,to observe the therapeutic effect of two groups were compared and the course of treatment.Results:1 patients in experimental group after treatment,patients with the total effective rate was 98(49/50),focus absorption rate was 52(26/50),significantly higher than that in the control group,P<0.05,the difference was statistically significant;the adverse reactions of patients in experimental group compared with the control,P>0.05,no difference statistical significance.Conclusion:the use of intravenous immunoglobulin protein combined with antibiotics on severe community acquired pneumonia treatment,good effect,and no increase in adverse reactions,is a better treatment plan

关 键 词：静脉免疫球蛋白 抗生素 重症获得性肺炎 临床疗效 

分 类 号：R563.1[医药卫生—呼吸系统]