长期应用丹参酮ⅡA可减缓OPCAB术后移植静脉桥狭窄  

Long Term Application of TanshinoneⅡA Can Reduce the Vein Graft Stenosis After OPCAB

作　　者：韩露[1] 张继倬[1] 陈兴华[1] 

机构地区：[1]首都医科大学附属北京世纪坛医院心外科,北京市100038

出　　处：《中国动脉硬化杂志》2015年第6期626-628,共3页Chinese Journal of Arteriosclerosis

摘　　要：目的研究丹参酮ⅡA对非体外冠状动脉旁路移植(OPCAB)术后移植静脉桥狭窄的影响。方法选取2006年~2010年OPCAB术后患者60例,随机分为丹参酮ⅡA组30例和对照组30例。随访3年后通过冠状动脉CT观察冠状动脉移植静脉桥的狭窄程度。结果丹参酮ⅡA组静脉桥的狭窄程度明显低于对照组(P<0.05)。结论丹参酮ⅡA可以延缓冠状动脉移植静脉桥狭窄。Aim To study the effect of tanshinone ⅡA on the vein graft stenosis after off-pumb coronary artery bypass grafting( OPCAB). Methods Sixty patients undergoing OPCAB from 2006 to 2010 were randomly divided into two groups treated with tanshinone ⅡA( 30 patients) or without tanshinone ⅡA( 30 patients). The vein graft stenosis was observed by CTA of heart after three years. Results The vein graft stenosis in the tanshinone ⅡA group was decreased as compared with the control group( P < 0. 05). Conclusion Long term application of tanshinone Ⅱ A can alleviate the vein graft stenosis after OPCAB.

关 键 词：丹参酮ⅡA 非体外冠状动脉旁路移植 静脉桥狭窄 

分 类 号：R654.2[医药卫生—外科学]